While not the first study to find that bariatric surgery may help reverse type 2 diabetes, a trial conducted by the Cleveland Clinic and published in the New England Journal of Medicine (NEJM), the STAMPEDE (Surgical Therapy and Medications Potentially Eradicate Diabetes Efficiently) trial, is the largest randomized trial to date.
For the study, which was also presented at the Annual Scientific Session of the American College of Cardiology in Washington, D.C., a third of patients underwent gastric bypass surgery with medications. Another third of patients in the study had a sleeve gastrectomy, and then took medications. The remaining third received only medications and psychological counseling.
Results showed that after three years, 37.5 percent of patients who had gastric bypass surgery were able to stabilize their blood sugar to healthy levels without medication; 24.5 percent of patients who underwent the sleeve gastrectomy were able to control their blood sugar without medications; while just five percent of patients who received only medication and counseling were able to successfully control their diabetes.
The researchers also found that participants who had bariatric surgery showed significant reduction in conditions associated with metabolic syndrome (a group of risk factors associated with obesity) including high blood pressure and poor kidney function. Only 5 to 10 percent of bariatric patients needed cardiovascular and glucose lowering medication, compared with 55 percent who only received medication and counseling.
The STAMPEDE trial was first published in the NEJM in 2012, but as this new data shows, the results have stood the test of 3 years’ time. No surgery is without risks, but for people with type 2 diabetes and metabolic syndrome, the benefits appear to be worth it.
If you are considering weight-loss surgery, contact Dr. Shawn Tsuda for a consultation.
Read more online at: https://weightloss.clevelandclinic.org/ClinicalTrials.aspx?MenuType=2